The expressions of stem cell markers: Oct4, Nanog, Sox2, nucleostemin, Bmi, Zfx, Tcl1, Tbx3, Dppa4, and Esrrb in bladder, colon, and prostate cancer, and certain cancer cell lines
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چکیده
منابع مشابه
The expressions of stem cell markers: Oct4, Nanog, Sox2, nucleostemin, Bmi, Zfx, Tcl1, Tbx3, Dppa4, and Esrrb in bladder, colon, and prostate cancer, and certain cancer cell lines
Uncontrolled self-renewal plays a direct function in the progression of different types of carcinomas. The same molecular pathway that manages self-renewal in normal stem cells also seems to manage cancer stem cells. Here, we examine the expressions of self-renewal regulatory factors Oct4, Nanog, Sox2, nucleostemin, Zfx, Esrrb, Tcl1, Tbx3, and Dppa4 in tissue samples of colon, prostate, and bla...
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متن کاملبیان ژن‌های خودبازسازی Oct4 ، Nanog ، Sox2 ، Nucleostemin ، Bmi و Zfx در رده‌های سلولی سرطانی کولون(CaCo2 و HT-29) ، کبد(HepG2)، پروستات (LNCaP)، مثانه(HT-1376) و در نمونه‌های تومور انسانی کولون، مثانه و پروستات
چکید ه سابقه و هدف ژن‌هایی که درکنترل خودبازسازی سلول‌های بنیادی نقش دارند به عنوان دسته جدیدی از مارکرهای مولکولی سرطان معرفی شده اند. در این تحقیق، بیان ژن‌های Oct4 ، Sox2 ، Nanog ، Nucleostemin ، Zfx و Bmi-1 در رده‌های سلولی سرطان کولون، پروستات، کبد و مثانه هم چنین در نمونه‌های انسانی این سرطان‌ها مورد بررسی قرار گرفت . مواد و روش‌ها در یک مطالعه تجربی، بیان ژن‌های خودبازسازی Oct4...
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ژورنال
عنوان ژورنال: Anatomy & Cell Biology
سال: 2014
ISSN: 2093-3665,2093-3673
DOI: 10.5115/acb.2014.47.1.1